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Late histopathologic characteristics of critically ill COVID-19 patients: Different phenotypes without evidence of invasive aspergillosis, A case series

Journal of Critical Care Jul 14, 2020

Flikweert AW, Grootenboers MJJH, Yick DCY, et al. - This study was intended to assess whether and how pathological data of critically ill COVID-19 patients is necessary for the search for optimal treatment options. The postmortem needle core lung biopsies were conducted in seven patients with COVID-19 related ARDS. Researchers reported clinical, radiological, and microbiological characteristics together with histopathological findings. The analysis enrolled five males and two females (patients ages ranged from 58 to 83 years). In critically ill COVID patients, in this case series common late histopathology is not classic DAD but heterogeneous with a predominant pattern of organizing pneumonia. Postmortem biopsy investigations in critically COVID-19 patients with probable COVID-19 Correlated pulmonary aspergillosis collected no findings for invasive aspergillosis.

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