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Laser trabeculoplasty for open-angle glaucoma: A systematic review and network meta-analysis

American Journal of Ophthalmology Sep 04, 2020

Zhou R, Sun Y, Chen H, et al. - Researchers conducted this systematic review and network meta-analysis to comprehensively assess the efficacy of different types of laser trabeculoplasty (LT) in the treatment of open-angle glaucoma. Eligible randomized controlled trials (RCT) have been identified by searching PubMed, EMBASE, Cochrane Library, SCOPUS, CNKI, and CBM for studies published between January 1, 2000, and April 20, 2020. Eight interventions were assessed which include argon LT (ALT), medications, 180° selective LT (SLT), 270° SLT, 360° SLT, new LT, transscleral 360° SLT with SLT performed without gonioscopy, and low-energy 360° SLT. A total of 22 studies were involved. Participants in the study were 2,704 patients (2,859 eyes). According to findings, all available types of LT are equally effective against medication-based therapy in decreasing IOP. In terms of reducing the number of medications required, the 180° SLT was slightly more effective than ALT. No severe adverse outcomes for any of the interventions have been reported.

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