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Large‐for‐gestational age diagnosed during second‐trimester anatomy ultrasound and association with gestational diabetes and large‐for‐gestational age at birth

Ultrasound in Obstetrics & Gynecology Dec 19, 2020

Rekawek P, Liu L, Getrajdman C, et al. - Researchers performed a retrospective cohort study of 756 patients with a large‐for‐gestational age (LGA) fetus and 756 with an appropriate‐for‐gestational‐age (AGA) fetus on second‐trimester ultrasound examination with the aim to determine if LGA diagnosed during second‐trimester ultrasound examination is linked with the development of gestational diabetes mellitus (GDM) and LGA at birth. The incidence of GDM was 6.0% and the incidence of LGA at birth was 14.9% in patients with a LGA fetus diagnosed during the second‐trimester ultrasound examination. Among patients with a LGA fetus in the second trimester, those who were significantly older and were obese developed GDM or LGA at birth more frequently. Observations overall revealed that the risk of developing GDM and LGA at birth is higher in correlation with LGA diagnosed during the second‐trimester ultrasound examination; this correlation was noted independent of known risk factors, and could be employed to recognize these women earlier for intervention.

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