Laparoscopic lavage vs primary resection for acute perforated diverticulitis: Long-term outcomes from the Scandinavian Diverticulitis (SCANDIV) randomized clinical trial
JAMA Surgery Feb 14, 2021
Azhar N, Johanssen A, Sundström T, et al. - The long-term (5-year) outcomes of laparoscopic peritoneal lavage vs primary resection as treatment of perforated purulent diverticulitis were compared. Researchers conducted an international multicenter randomized clinical trial in 21 hospitals in Sweden and Norway including 145 patients at a Hinchey stage less than IV (73 with laparoscopic lavage and 69 with resection; 3 lost to follow-up). Treatment groups had no differences in terms of severe complications, mortality, functional outcomes, or quality of life over a median of 59 months of follow-up. More stomas were identified in the resection group. Findings from this trial thereby suggest achievement of comparable long-term results with performing laparoscopic lavage vs primary resection in the treatment of perforated purulent diverticulitis.
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