Lu J, et al. - The relationship between serum lactate dehydrogenase (LDH) and 28-day mortality was examined in a total of 192 patients with sepsis. Researchers collected data on characteristics of patients, biochemical variables, and inflammatory mediator. Elevated LDH group and normal LDH group showed statistical differences in 28-day mortality. Among patients with sepsis, level of serum LDH was an independent risk factor for death. Significant correlations between LDH, interleukin-1β, creatinine, PaO₂/FiO₂, and lactate were identified. Outcomes thus suggest a probable correlation between serum LDH and 28-day mortality in patients with sepsis.