Yang C, et al. - This study focused on the links between kidney function, bone-mineral metabolism (BMM) markers and future risk of peripheral artery disease (PAD). Findings demonstrated an independent association of kidney dysfunction with future PAD risk, specifically when evaluated with cystatin C and beta-2 microglobulin (B2M). Phosphorus was identified as the only BMM marker strongly associated with incident PAD beyond kidney function. This study indicates that novel filtration markers may be a potentially useful tool for PAD risk assessment and phosphorus may be involved in the pathophysiology of PAD.