Malmgren L, et al. - In the OPRA cohort, a longitudinal study of elderly non-selected women, experts examined the association between kidney function and fracture. Estimates of cystatin C–based kidney function were available at age 75 (n = 981) and 80 (n = 685). Elderly women with a mild-moderate decrease of kidney function were at heightened risk of fractures, however, not those with the worst function. Findings, moreover, validated the value of osteoporosis evaluation and there is a possibility that in this age group, age-related deterioration of kidney function has limited contribution in comparison with BMD.