Thuluvath PJ, et al. - Whether Karnofsky Performance Status (KPS) is an independent predictor of post-liver transplant (LT) survival after adjusting for known confounders, was determined in this investigation. The trends in KPS before and after LT and survival probabilities based on KPS were determined. It was observed in the findings that there was a decline in KPS scores between listing and liver transplantation. A significant improvement after liver transplantation was also noted. Before and after LT, the KPS was an independent predictor of graft and patient survival after adjusting for other important predictors of survival.