Schousboe JT, Langsetmo L, Szulc P, et al. - This study was conducted to calculate the individual and joint associations of prevalent vertebral fractures (PVFx) and abdominal aortic calcification (AAC) with incident major osteoporotic, hip, and clinical vertebral fractures in 5365 older men enrolled in the Osteoporotic Fractures in Men Study, using Cox proportional hazards and Fine and Gray subdistribution hazards models to account for competing mortality. Researchers determined PVFx (Genant SQ grade 2 or 3) and 24‐point AAC score on baseline lateral spine radiographs. Compared with men with either risk factor alone, older men with both PVFx and a high level of AAC are at higher risk of incident major osteoporotic fracture. This study’s findings demonstrate that evaluating prevalent radiographic vertebral fracture and AAC on the same lateral spine images may improve the prediction of older men who will have an incident major osteoporotic fracture, even after accounting for traditional fracture risk factors and competing mortality.