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IV levetiracetam vs IV phenytoin in childhood seizures: A randomized controlled trial

Journal of Pediatric Neurosciences Jul 09, 2018

Singh K, et al. - The efficacy of IV phenytoin and IV levetiracetam in acute seizures were compared in this randomized controlled trial. Participants in the study were 100 children aged 3–12 years of age presenting with acute seizures from November 2012 to April 2014. For this investigation, study participants were randomized to receive either IV phenytoin 20mg/kg (n=50) or IV levetiracetam 30mg/kg (n=50). In children 3–12 years presenting with acute seizures, intravenous levetiracetam and phenytoin had similar efficacy in preventing seizure recurrences for 24 hours.

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