Charan J, et al. - Researchers searched PubMed, Cochrane Clinical Trial Registry and Google Scholar from inception to December 2016 to evaluate the efficacy of isoniazid for the prevention of tuberculosis (TB) in children living with HIV (CLHIV) through a systematic review and meta-analysis. Eligibility criteria for inclusion incorporated any randomized controlled trial assessing the role of isoniazid for the prevention of TB in CLHIV. It was observed that isoniazid did not decrease the incidence of TB in CLHIV.