Iguchi M, Kato T, Yaku H, et al. - During hospitalization for acute decompensated heart failure (ADHF), the incidence of ischemic stroke is not rare and it develops as a serious complication, therefore, prevention of ischemic stroke merits more attention when treating patients with ADHF.

• Using a multicenter registry of 4,056 patients with ADHF in Japan, the incidence as well as predictors of ischemic stroke during hospitalization for ADHF were investigated.

• Ischemic stroke occurred in 1.6% of the patients during hospitalization for ADHF.

• Factors independently related to ischemic stroke included men (OR, 1.87), ACS (OR, 2.31), absence of prior HF hospitalization (OR, 2.21), and high B‐type natriuretic peptide/N‐terminal proBNP levels (above the median) at admission (OR, 3.15).

• Higher in‐hospital mortality, longer length of hospital stay, and poorer functional status at discharge were evident in patients with ischemic stroke.