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Is there association between statin usage and contrast-associated acute kidney injury after intravenous administration of iodine-based contrast media in enhanced computed tomography?

European Radiology Sep 12, 2020

Park JH, Shin HJ, Choi JY, et al. - This study was intended to assess is there an association between statin usage and contrast-associated acute kidney injury after intravenous administration of iodine-based contrast media in enhanced computed tomography. Researchers retrospectively included a total of 12,371 patients who had undergone contrast-enhanced abdominopelvic CT and stratified into statin users and statin non-users. They performed subgroup analyses comparing high-intensity statins with low- to moderate-intensity statins within statin users and similar comparisons were conducted within statin users stratified based on baseline eGFR. The results of this study indicated that statin was not significantly correlated with the risk of contrast-induced acute kidney injury (CI-AKI) events in patients undergoing contrast-enhanced abdominopelvic CT and high-intensity statins did not exhibit a significant relationship with CI-AKI over low- to moderate-intensity statins in the subgroup analysis.

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