Is there association between statin usage and contrast-associated acute kidney injury after intravenous administration of iodine-based contrast media in enhanced computed tomography?
European Radiology May 15, 2020
Park JH, Shin HJ, Choi JY, et al. - Given contrast-induced acute kidney injury (CI-AKI) represents one of the main reasons for new-onset renal failure among hospitalized patients, and although statin has been assessed for its protective impact against CI-AKI but rarely it has been evaluated among patients receiving intravenous administrations of iodine-based contrast media for enhanced computed tomography (CT), therefore, researchers retrospectively analyzed 12,371 patients who had contrast-enhanced abdominopelvic CT and stratified into statin users and statin nonusers. Overall, no significant link of statin with the risk of CI-AKI events was identified among patients undergoing contrast-enhanced abdominopelvic CT, and subgroup analysis revealed no significant link of high-intensity statins with CI-AKI over low- to moderate-intensity statins.
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