Pereira J, et al. - This study was performed to determine the best high sensitivity C-reactive protein (hsCRP) cut-off for infection prediction in acute heart Failure (HF). Researchers suggested 25 mg/L as a cut-off beyond which an infection should be sought underlying acute HF. No infection was detected in almost 80% of the patients with hsCRP<25 mg/L. A concomitant infection was noted in 69.4% of those with higher hsCRP.