Shariq OA, Bews KA, McKenna NP, et al. - The outcomes and trends of ambulatory laparoscopic adrenalectomy were examined in a multicenter cohort of patients. Querying database of the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP), researchers included 4,807 patients in the study; of these, 88 (1.8%) underwent ambulatory laparoscopic adrenalectomy and 4,719 (98.2%) were admitted after the adrenalectomy. Relative to the inpatient group, the same-day discharge group contained fewer obese patients, a lesser proportion of American Society of Anesthesiologists class III patients, and more patients with primary aldosteronism. After adjustment for confounders, no association of same-day discharge with 30-day overall complications or unplanned readmissions. With no evidence of an increasing trend over time, continually low percentage of laparoscopic adrenalectomies were performed on an ambulatory basis at hospitals participating in the ACS NSQIP throughout the study period . Findings support the safety and feasibility of ambulatory laparoscopic adrenalectomy as an alternative to inpatient hospitalization in selected patients.