Solini A, et al. - In this investigation, researchers ascertained if resistant hypertension is an independent predictor of all-cause mortality in people with type 2 diabetes from the Renal Insufficiency And Cardiovascular Events (RIACE) Italian Multicentre Study. Vital status information was retrieved for 15,656 participants enrolled in 2006–2008. Crude mortality rates and Kaplan–Meier estimates were the highest among participants with resistant hypertension, particularly those with controlled resistant hypertension, using the categorization targets of 130/80 mmHg. Resistant hypertension did not predict death beyond target organ damage in the RIACE cohort, in contrast to the general hypertensive population. The study findings may be explained by the high risk of mortality from type 2 diabetes and the low blood pressure (BP) values observed in controlled hypertensive patients, which may mask the risk related to resistant hypertension. In high-risk patients with type 2 diabetes, less stringent BP goals may be preferable.