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Is placental malaria a long-term risk factor for mild malaria attack in infancy? Revisiting a paradigm

Clinical Infectious Diseases Mar 14, 2018

Bouaziz O, et al. - Researchers designed this work to assess if children born to mothers with placental malaria (PM) are more susceptible to malaria and remain at higher risk between birth and 18 months. Findings suggested that PM was not associated with an overall susceptibility to malaria but only with the delay of occurrence of the first malaria attack. An increased risk for the first malaria attack but not for subsequent ones was identified among children born from mothers with PM. Children who experienced 1 malaria attack were strongly at risk to develop subsequent infections independent of placental infection and environmental exposure.
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