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Is elevation of N-terminal pro-B-type natriuretic peptide at discharge associated with 2-year composite endpoint of all-cause mortality and heart failure hospitalisation after transcatheter aortic valve implantation? Insights from a multicentre prospective OCEAN-TAVI registry in Japan

BMJ Open Aug 23, 2018

Mizutani K, et al. - In this multicenter prospective observational study, researchers examined the 2-year prognostic impact of N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels at discharge following transcatheter aortic valve implantation (TAVI) by analyzing data of 500 consecutive patients who had TAVI with measurements of NT-proBNP at discharge between 2013 and 2016. The findings from the present study suggested that elevation of NT-proBNP at discharge was related to higher incidence of the 2-year composite endpoint (all-cause mortality and heart failure hospitalization) after TAVI.

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