Zuckerman MJ, et al. - A survey was conducted in a randomly selected indigent population recruited into a colon cancer screening program (ACCION) to study the prevalence of irritable bowel syndrome (IBS), and its relationship with health perception and health care–seeking behavior in this Mexican American population. Results revealed that country of birth was Mexico in 90.5% and the United States in 8.2% and acculturation was more Spanish (94.8%) than English (5.2%). In both countries, the prevalence of IBS on the US Mexico border was comparable with data obtained from studies. Findings revealed that consulting a primary care physician as an associated factor might reveal the high rate of health-care seeking in IBS patients. On the other hand, herbal treatments might reflect a cultural influence.