Chu H, et al. – In the study presented here, the researchers examined the role of chemokines in proliferation and migration of tongue squamous cell carcinoma (TSCC). They observed that the expression of macrophage inflammatory protein-3α (MIP-3α), macrophage inflammatory protein-1β (MIP-1β), and interferon gamma-induced protein 10 (IP-10) increased in the TSCC cells and the elevated expression of MIP-3α and IP-10 promoted proliferation and migration of TSCC. These chemokines, along with their receptors, could be potential biomarkers and therapeutic targets for TSCC, particularly for those in the high clinical stages.