Sivasundaram L, Raji Y, Mengers SRP, et al. - In this study, the relationship of preoperative international normalized ratio (INR) with rates of transfusion, complication, and readmission/revision surgery in shoulder arthroplasty was investigated. Researchers distinguished individuals who had undergone elective shoulder arthroplasty were identified in a national database. They further assessed major and minor complications, revision surgery, and readmission rates. They distinguished 1,014 procedures who had undergone elective shoulder arthroplasty with a perioperative INR lab result within 24 hours of surgery between 2006 and 2016. The outcomes did not find an elevated risk for bleeding and complication with an INR ≤ 1.5 for shoulder arthroplasty, although recent hip and knee arthroplasty literature has found that an INR < 1.25 may be an optimal preoperative INR goal. The findings support recent guidelines recommending a preoperative INR ≤ 1.5 for shoulder arthroplasty.