Fouladi DF, et al. - This study was carried out to correlate the CT features of colloid carcinoma and tubular adenocarcinoma of the pancreas arising in relationship with intraductal papillary mucinous neoplasms (IPMNs). Researchers retrospectively examined the preoperative CT images of 85 patients with histopathologically proven IPMNs and associated invasive adenocarcinoma located next to each other. They included 29 individuals (34.1%; 19 men and 10 women; mean [± SD] age, 68.0 ± 9.5 years) with invasive colloid carcinoma and 56 patients (65.9%; 31 men and 25 women; mean age, 70.8 ± 10.6 years) with invasive tubular adenocarcinoma. Between the two groups, they compared the following CT features: IPMN type, main pancreatic duct (MPD) and common bile duct (CBD) diameters, diameter and characteristics of the largest cystic lesion for branch duct and mixed-type IPMNs, presence of an extracystic or extraductal solid mass next to the cystic lesion or MPD, morphologic features of the upstream MPD in relation to the cystic lesion or solid mass, and presence of a fistula to the adjacent organs. The results showed that preoperative CT is important in differentiating two types of invasive carcinoma arising in correlation with IPMNs. These findings are clinically significant because the prognosis is better for colloid carcinoma than for tubular adenocarcinoma.