Olbrecht VA, et al. - The impact of intravenous acetaminophen (IV APAP) on length of hospital stay (LOS) via mediation of opioid-related side effects in pediatric patients was determined in this analysis. Researchers prospectively recruited one hundred fourteen adolescents undergoing posterior spinal fusion and managed postoperatively with patient-controlled analgesia and adjuvant therapy after Institutional Review Board approval. The present data indicated that IV APAP hastens oral intake and was linked with reduced LOS in an adolescent surgery population likely through decreased opioid consumption. Findings suggested that LOS could be decreased through the addition of IV APAP in this population, an important implication in the setting of escalating health care costs.