Masumoto N, et al. - Researchers investigated whether there was an association between ¹⁸F-fluorodeoxyglucose (FDG) uptake on dedicated breast positron emission tomography (DbPET) and the clinicopathological features of breast cancer, especially those with an intratumoral heterogeneous distribution of FDG on DbPET. In total, 195 consecutive patients with invasive breast cancer who had a preoperative whole-body PET (WBPET) and DbPET concurrently between January 2016 and March 2017 were evaluated. Data reported that the maximum standard uptake values of DbPET correlates with clinicopathological factors, as does WBPET. The study findings suggested that intratumoral heterogeneity on DbPET offers prognostic value for malignancy grade and could help with therapeutic decisions.