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Intrathecal catheterisation after observed accidental dural puncture in labouring women: Update of a meta-analysis and a trial-sequential analysis

International Journal of Obstetric Anesthesia Feb 10, 2020

Heesen M, Hilber N, Rijs K, et al. - Since it has been demonstrated in experts' meta-analysis from 2013 that the requirement for epidural blood patch among labouring women requesting epidural analgesia can be reduced by inserting a catheter intrathecally following an observed accidental dural puncture, researchers updated their conventional meta-analysis as well as added a trial-sequential analysis (TSA). Investigations comparing inserting the catheter intrathecally with an epidural catheter re-site or with no intervention were selected via a systematic literature exploration. Experts found 13 studies with 1,653 patients. For the first time, it was demonstrated by conventional meta-analyses that post-dural puncture headache incidence can be reduced by adopting intrathecal catheterisation. However, this finding was not confirmed in the TSA. Despite growing use in clinical practice, no firm evidence was found on which to base a definite conclusion.
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