Mei B, et al. - Researchers examined patients 65 years of age or older who had total hip arthroplasty between June 2016 and June 2017, to determine the impact of intraoperative sedation with dexmedetomidine on the prevalence of postoperative delirium (POD) when administered as a supplementary to peripheral nerve block for total hip arthroplasty. Participants randomly received a lumbosacral plexus plus T12 paravertebral block supplemented with propofol or dexmedetomidine for sedation. Findings showed intraoperative sedation with dexmedetomidine, as a supplementary to peripheral nerve block, could be related to a lower incidence of POD. Due to this, the incidence of early postoperative cognitive dysfunction may be reduced and a better short-term recovery may be achieved subsequently.