Villarreal JA, et al. - Because children undergoing liver transplantation are at significant risk of intraoperative hemorrhage and thrombotic complications, researchers identified novel risk factors in PLT recipients for massive intraoperative blood loss and transfusion and characterized their impact on graft survival and hospital LOS. Between September 2007 and September 2016, all primary PLTs performed at the institution were reviewed. Upon backward stepwise regression, significant independent risk factors for massive EBL and MT were technical variant graft, operative time, and transfusion of FFP, platelet, and/or cryoprecipitate, while home admission was a protective factor. For MT alone, the recipient weight was an important independent risk factor. For overall graft survival, massive EBL and MT were not statistically significant. However, MT was a significant risk factor for 30-day graft loss. In patients requiring MT, PLT recipients with massive EBL or MT had significantly longer LOS and increased 30-day graft loss.