Intramucosal colorectal carcinoma with lymphovascular invasion: Clinicopathological characteristics of 9 cases
Histopathology Jan 24, 2019
Hashimoto H, et al. - In this investigation, researchers evaluated the pathological features of intramucosal colorectal carcinomas (CRCs) with lymphovascular invasion and if lymph node metastasis is an indication for additional surgery. In order to determine the histological features of intramucosal CRCs with lymphovascular invasion, several features were analyzed and their incidence in 9 cases and 20 other intramucosal CRCs without lymphovascular invasion assessed. High-grade tumor budding and the “eosinophilic cytoplasm and round nuclei with inflammatory reaction” pattern are morphological features that are different from those of noninvasive CRC, which is tantamount to high-grade dysplasia in intramucosal CRCs with lymphovascular invasion. None of the seven lymph node-dissected cases of intramucosal CRCs with lymphovascular invasion showed metastasis of the lymph node.
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