Sekhon MS, et al. - Researchers sought to characterize the temporal trends and patterns of increased intracranial pressure (ICP) and compliance in human hypoxic ischemic brain injury (HIBI) patients. They performed invasive ICP monitoring with a parenchymal probe (Camino) on ten patients [median age: 47 (range 20 – 71) and seven males (7/10)] and managed them with a tier-based management algorithm for elevated ICP. As per observations, HIBI patients had normal ICP but with limited intracranial compliance. However, there was significant in between patient heterogeneity regarding temporal patterns of intracranial pressure-volume relationships in HIBI.