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Intracranial aneurysm is predicted by abdominal aortic calcification index: A retrospective case-control study

Atherosclerosis Aug 19, 2021

Rantasalo V, Gunn J, Kiviniemi T, et al. - According to this retrospective case-control study, patients with ruptured intracranial aneurysms (rIA) and unruptured intracranial aneurysms (UIA) have more aortic calcification than matched controls. Aortic calcification index (ACI) raises the risk of rIAs.

  • A total of 462 patients with abdominal CT were selected from a total of 2,020 IA patients.

  • One thousand seven hundred twenty patients (216 rIA, 246 UIA and 1,258 control) were involved.

  • The average age was 62.9 ± 11.9 years and 58.2% were female.

  • When compared with matched controls, ACI and ACI > 3 increased the risk of rIA.

  • UIA patients' ACI was significantly higher but ACI did not increase chances for UIA when compared with matched controls.

  • In rIA patients, a history of coronary artery disease was less common.

  • In 8.8% rIA and 13.6% UIA patients, there was no aortic calcification.

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