Cohen B, et al. - In this posthoc subanalysis of a large alternating cohort trial, researchers investigated whether intra-operative FiO₂ (inspired oxygen fraction) of 80% vs 30% inspired oxygen decreases the postoperative ratio of arterial saturation to fraction of inspired oxygen (SpO₂/FiO₂). They also determined if the incidence of pulmonary complications is increased by an intra-operative inspired FiO₂ of 80%. This study included adults having colorectal surgery. The excluded cases were those that lasted less than 2 h, re-operations on the same hospitalisation, and cases with missing intra-operative or postoperative data. According to findings, the postoperative SpO₂/FiO₂ ratio or the risk for pulmonary complications was not altered by intra-operative hyperoxia.