Colen S, Hoorntje A, Maeckelbergh L, et al. - The present study was conducted to assess the influence of intra-articular hyaluronic acid (IAHA) on the outcome of total hip arthroplasty (THA), with an emphasis on the periprosthetic joint infection (PJI). In this study, complication rates, including superficial and deep PJIs, of THA were compared in patients who received an IAHA injection ≤ 6 months prior to surgery (injection group) with that of patients undergoing THA without any previous injection in the ipsilateral hip (control group) at a mean follow-up of 52 months (±18). Researchers enrolled 113 patient (118 hips) in the injection group and 452 patients (495 hips) in the control group. The data imply that IAHA conducted 6 months or less prior to THA may pose a risk for elevated rates of PJI. They proposed refraining from conducting THA within 6 months after IAHA administration.