Korivi BR, et al. - In this retrospective IRB-approved study involving 99 treatment-naïve patients, researchers evaluated variances in primary sites and spread patterns of intestinal and diffuse subtypes of gastric carcinoma, and if survival outcomes were based on spread patterns. For this investigation, they used Pearson's chi-squared test to correlate tumor pathology with metastatic sites. Findings revealed that the intestinal subtype was significantly linked to hepatic metastases, while diffuse subtype was related to peritoneal metastases, including omental metastases, gastrosplenic ligament involvement, and mesocolonic implants. Compared to patients with primary sites at the antrum, GE junction and lesser curvature, those with primary gastric tumors at the greater curvature had longer overall survival. Findings suggested that recognizing distinctive spread patterns for intestinal vs diffuse gastric carcinoma can help radiologists in diagnosing and guiding clinical management. Survival was not impacted by the presence of hepatic metastases.