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Interval between debulking surgery and adjuvant chemotherapy is associated with overall survival in patients with advanced ovarian cancer

Gynecologic Oncology Jul 17, 2018

Timmermans M, et al. - Researchers investigated the impact of time from surgery to adjuvant chemotherapy (TTC) on clinical outcome in all Dutch patients who received optimal or complete debulking surgery for primary epithelial ovarian cancer (EOC) (FIGO IIb-IV) between 2008 and 2015. They used the Netherlands Cancer Registry to identify these patients. They found that worse overall survival after complete (interval) debulking surgery was independently predicted by delayed initiation of adjuvant chemotherapy and therefore, initiating adjuvant chemotherapy within five to six weeks after debulking surgery was recommended.

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