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International trends in the incidence of testicular cancer: Lessons from 35 years and 41 countries

European Urology Jul 23, 2019

Gurney JK, et al. - Cancer registry data from Cancer Incidence in Five Continents volumes V–XI, CI5plus, and the NORDCAN database were evaluated by the experts in order to present incidence data from 41 countries and assess incidence trends of testicular cancer (TC) for the 35-yr period from 1978 to 2012. Age-standardized rates of TC overall and by histological type were estimated. The gap closed between higher- and lower-incidence regions, while the maximum incidence of TC persisted in Northern Europe. A constant rise in risk in the USA (particularly for seminomas), and an elevation in risk among more recent cohorts in Costa Rica, Croatia, and Slovakia was observed in the UK and age-period-cohort modeling was discovered to be flattening of risk among recent cohorts in Denmark. Hence, the gap between low- and high-incidence countries was concluded to be closing due to elevations in the former and stabilization in the latter. Countries may help more our understanding of the etiology of this cancer, knowing the reasons for these and other variations in incidence rates between, and within.
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