Randle JM, et al. - Researchers conducted a scoping review of 28 articles in order to investigate the temporal association between antipsychotic use and mortality risk for older institutionalized adults. Older adults with dementia exhibited a higher risk of mortality when received antipsychotic medications. Compared to atypical preparations, conventional antipsychotics present a higher risk. Within 30 to 40 days of initiating antipsychotic treatment, mortality risk seems highest. Some previously unrecognized illness, comorbidity, change in health status, or increased frailty, rather than an idiosyncrasy of the antipsychotic itself, seemed actually attributing to the increased mortality.