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Interaction of ischaemic postconditioning and thrombectomy in patients with ST-elevation myocardial infarction

Heart Aug 07, 2019

Nepper-Christensen L, Høfsten DE, Helqvist S, et al. - Among patients included in DANAMI-3-iPOST (The Third Danish Study of Optimal Acute Treatment of Patients with ST-segment Elevation Myocardial Infarction – Ischaemic Postconditioning), stratified by the use of thrombectomy, researchers assessed the influence of ischemic postconditioning. A combination of all-cause death and hospitalization for heart failure was assessed as the primary endpoint in ST-segment elevation myocardial infarction (STEMI) patients randomized to conventional primary percutaneous coronary intervention (PCI) or ischemic postconditioning with primary PCI. Findings of this posthoc analysis of DANAMI-3-iPOST revealed lower risk of all-cause mortality and hospitalization for heart failure in relation to ischemic postconditioning in addition to primary PCI in patients with STEMI not treated with thrombectomy.

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