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Interaction between caffeine and polymorphisms of glutamate ionotropic receptor NMDA type subunit 2A (GRIN2A) and cytochrome P450 1A2 (CYP1A2) on Parkinson's disease risk

Movement Disorders Jan 13, 2018

Kim IY, et al. - Here, the physicians intended to explore the interaction of caffeine intake with glutamate ionotropic receptor NMDA type subunit 2A (GRIN2A)-rs4998386 and cytochrome P450 1A2 (CYP1A2)-rs762551 polymorphisms in influencing Parkinson's disease (PD) risk. No interaction was found between the GRIN2A-rs4998386 or CYP1A2-rs762551 polymorphism and caffeine intake in determining PD risk.
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