Chung JW, Cha J, Lee MJ, et al. - Since several studies have shown the effects of statin treatment on plaques of coronary and carotid arteries, researchers analyzed the impact of statin treatment on plaques of intracranial atherosclerosis. The study sample consisted of 77 patients (mean age: 62.6 ± 13.7 years). Higher reduction of LDL cholesterol and longer duration of statin treatment were linked to reduced enhancement volume after statin treatment. As documented by HR-MRI, high-dose statin therapy efficiently stabilized symptomatic intracranial atherosclerotic plaques. For these patients, further research is required to identify laboratory and genetic factors connected with poor statin response and alternative therapeutic choices.