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Intensity modulated radiation therapy may improve survival for tracheal- bronchial adenoid cystic carcinoma: A retrospective study of 133 cases

Lung Cancer May 12, 2021

Yang Y, Ran J, Wang Y, et al. - Researchers sought to determine the impact of radiotherapy (RT) and intensity modulated radiation therapy (IMRT) in adjuvant and definitive settings of tracheal-bronchial adenoid cystic carcinoma (TACC) treatment. They retrospectively examined 133 TACC patients who were managed with surgery and/or RT curatively. There were 116 patients receiving surgery, of those, 50 (43.1%) attained complete resections and 66 (56.9%) had positive surgical margins. Findings revealed that greatly improved OS and LRFS could be achieved with IMRT use in postoperative setting for TACC patients with positive surgical margins. Promising survival and local control was also conferred by IMRT for definitive TACC, showing utility as a good therapeutic option for such cases.

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