Burt MG, Mangelsdorf BL, Drake SM, et al. - In this case-control and prospective single-arm study involving 16 women with breast cancer and 17 control individuals, triglycerides were higher in breast cancer patients before treatment, and insulin sensitivity and bone mass were reduced after treatment.

• Between patients with breast cancer and controls, there were no significant differences in age (53 ± 9 vs 54 ± 11 years) or BMI (28 ± 7 vs 28 ± 6).

• Triglycerides were higher in breast cancer patients than in controls (1.2 ± 0.1 vs 0.8 ± 0.1 mmol/L), but there were no significant differences in Matsuda index, pulse wave velocity, or reactive hyperaemia index.

• There was a lower Matsuda index (6.3 ± 1.2 vs 5.2 ± 1.0) after cancer treatment, but this was not related to a significant change in vascular function.

• After cancer treatment, bone mass decreased by 3%, from 2.27 ± 0.11 to 2.20 ± 0.10 kg.