Min JY, et al. - Researchers contemplated the existence of a connection between smell dysfunction with diabetes mellitus (DM)-related biomarkers, including fasting blood glucose, glycohemoglobin, serum insulin, and homeostasis model assessment of insulin sensitivity (HOMA-IR), among older US adults. Results exhibited a prominent correlation between smell dysfunction and severe insulin resistance in the study cohort. It was deduced that insulin resistance could be mechanistically associated with the loss of smell function.