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Inner nuclear layer cystoid spaces are a poor prognostic factor in typical age-related macular degeneration and polypoidal choroidal vasculopathy

Graefe's Archive for Clinical and Experimental Ophthalmology Oct 18, 2017

Kang EC, et al. - The target herein was to contemplate the predictive factors for variations in best-corrected visual acuity (BCVA) at 24 months after intravitreal ranibizumab (IVR), for neovascular age-related macular degeneration (nAMD). The results displayed that eyes with cystoid spaces in the inner nuclear layer (INLc) or thinned subfoveal choroidal thickness (SFCT) presented with worse visual outcomes, in contrast, with eyes without the INLc or with thick SFCT. An improvement was gained in the BCVA in eyes without INLc. Nonetheless, eyes with INLc illustrated decreased BCVA with an as-needed regimen.
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