Hassan H, et al. - Researchers conducted this single‐center, prospective, uncontrolled study to assess the effectiveness of injectable platelet rich fibrin (i‐PRF) for facial skin rejuvenation utilizing an objective skin analysis system and validated patient‐reported outcome measures. They used PRF® PROCESS system technology to prepare i‐PRP. Participants in the study were 11 healthy female individuals and over 3‐months got monthly intradermal injections of i‐PRF in 3 facial regions: malar areas (1 mL each side), nasolabial fold (0.5 mL each side), and upper lip skin above the vermilion border (1 mL). The 3-month follow-up showed a significant improvement in skin surface spots and pores. Other variables like skin texture, wrinkles, UV‐spots, and porphyrins, exhibited a numerical improvement. A series of three i‐PRF injections led to a significant rejuvenation of the face skin at a 3‐month follow‐up, as evidenced by improved skin analysis parameters and self‐assessment scores for patients. No major adverse effects have been reported.