Eskesen TG, et al. - A systematic review was conducted to identify and summarise the evidence for supplementary oxygen for spontaneously breathing trauma patients and for high (0.60–0.90) vs low (0.30–0.50) inspiratory oxygen fraction (FiO₂) for intubated trauma patients in the initial phase of treatment. Sixty-eight trauma subjects were randomised to receive an FiO₂ of 0.80 (intervention group) or 0.50 (control group) during mechanical ventilation (first 6 hours). Researchers reported that evidence for the use of supplementary oxygen for spontaneously breathing trauma patients was lacking. In addition, the evidence for low vs high FiO₂ for intubated trauma patients was limited.