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Infrared thermography and ulcer prevention in the high-risk diabetic foot: Data from a single-blind multicentre controlled clinical trial

Diabetic Medicine Oct 25, 2019

Petrova NL, Donaldson NK, Tang W, et al. - Researchers conducted this single-blind multicentre clinical trial, at three clinical centres in the UK from March 2016 to September 2017 to evaluate the usefulness of monthly thermography and standard foot care to lessen diabetic foot ulcer recurrence. Participants in the study were individuals with diabetes (n = 110), neuropathy and history of ≥ 1 foot ulcer. With a novel thermal imaging device (Diabetic Foot Ulcer Prevention System), feet were imaged. According to results, 62% of participants were ulcer-free in the intervention group and 56% in the control group after 12 months. In univariate and multivariate logistic regression analyses, respectively, the odds ratios of ulcer recurrence (intervention vs control) were 0.82 and 0.55 and the hazard ratios for the time to ulcer recurrence (intervention vs control) were 0.84 and 0.67. In this cohort at high risk of foot ulcers, monthly intervention with thermal imaging did not result in a significant decrease in ulcer recurrence rate or increased ulcer-free survival. However, this trial informed the design of a refined study with longer follow-up and group stratification, further aiming to evaluate the effectiveness of thermography to reduce the recurrence of ulcer.
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