Spagnolo F, Boutros A, Croce E, et al. - A systematic review was conducted to evaluate the safety and efficacy of influenza vaccination in cancer patients receiving immune checkpoint inhibitors. Researchers included studies reporting safety and efficacy outcomes of influenza vaccination in cancer patients receiving immune checkpoint inhibitors. They conducted only descriptive statistics to collect a pooled rate of immune-related adverse events in vaccinated patients. In this research, ten studies evaluating the safety and eight measuring the effectiveness of influenza vaccination in cancer patients receiving immune checkpoint inhibitors were distinguished, for a total of 1,124 and 986 vaccinated patients, respectively. The outcomes reveal the safety and efficacy of influenza vaccination in cancer patients receiving immune checkpoint inhibitors. These outcomes are especially relevant in the context of the SARS-Cov-2 pandemic.