Hellak A, et al. - Researchers used three-dimensional datasets to distinguish connections between treatment for adult crowding, using Invisalign aligner and interproximal enamel reduction (IER), and changes in the volume of interradicular bone. In order to measure bone volume three-dimensionally, they retrospectively examined 60 cone-beam computed tomography (CBCT) scans from 30 adult patients (28 women, two men; 30 CBCTs pre-treatment, 30 post-treatment). Findings suggested that treatment of adult crowding using Invisalign and IER, especially in subjects with severe conditions (with periodontally high-risk dentition), seems to have a positive effect on the interradicular bone volume, at least in adult female patients. They reported that the effect was also apparently independent of IER.