Kim HJ, et al. - Researchers examined how preoperative glycated hemoglobin (HbA1c) level in patients with diabetes mellitus undergoing off-pump coronary bypass (OPCAB) influence perioperative glycemic variability and short-term outcome. They reviewed medical records of 703 patients with diabetes mellitus who underwent OPCAB from 2005 to 2017 and identified the greater incidence of the composite of postoperative morbidity and mortality endpoints in patients with HbA1c ≥7.0% (21% vs 15%). This suggests an adverse influence of increased preoperative HbA1c (≥7.0%) level reflecting long-term glycemic control on the outcome in patients with diabetes mellitus undergoing OPCAB. However, there appeared nullification of the influence of perioperative glycemic variables using a target glucose level of <180 mg/dL.